It looks to me like your issue is not focus, but noise--I would suggest using the lowest ISO speed you can use and still get a fast enough shutter speed for hand-held. (Actually, this is sort of true generally.) I leave my camera set on 100 pretty much all the time unless I'm trying to freeze fast motion or working in low light. Depending on how dim it was and your camera, you might be able to use 200, and I would avoid going higher than 400.
Also depending on your camera, it may have a "noise reduction at high ISO speeds" setting, which is good to turn on.
no subject
It looks to me like your issue is not focus, but noise--I would suggest using the lowest ISO speed you can use and still get a fast enough shutter speed for hand-held. (Actually, this is sort of true generally.) I leave my camera set on 100 pretty much all the time unless I'm trying to freeze fast motion or working in low light. Depending on how dim it was and your camera, you might be able to use 200, and I would avoid going higher than 400.
Also depending on your camera, it may have a "noise reduction at high ISO speeds" setting, which is good to turn on.